Intermittent hypoxia and neurorehabilitation

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Intermittent hypoxia and neurorehabilitation.

In recent years, it has become clear that brief, repeated presentations of hypoxia [i.e., acute intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in certain cases of neurologic dysfunction. This hypothesis derives from a series of studies in animal models and human subjects performed over the past 35 yr. In 1980, Millhorn et al. (Millhorn DE, Eldridge...

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Intermittent hypoxia reduces microglia proliferation and induces DNA damage in vitro

Objective(s):Intermittent hypoxia (IH), caused by obstructive sleep apnea (OSA), could cause hippocampus or neuron damage through multiple signaling pathways, while the underlying mechanisms are still unclear. Thus, the present study aimed to explore the effect of IH on the biological functions of microglia cells. Materials and Methods:Cell proliferation of BV2 cells after exposure to IH were o...

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Physiological and Genomic Consequences of Intermittent Hypoxia Invited Review: Intermittent hypoxia and respiratory plasticity

Mitchell, Gordon S., Tracy L. Baker, Steven A. Nanda, David D. Fuller, Andrea G. Zabka, Brad A. Hodgeman, Ryan W. Bavis, Kenneth J. Mack, and E. B. Olson, Jr. Invited Review: Intermittent hypoxia and respiratory plasticity. J Appl Physiol 90: 2466–2475, 2001.— Intermittent hypoxia elicits long-term facilitation (LTF), a persistent augmentation (hours) of respiratory motor output. Considerable r...

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Physiological and Genomic Consequences of Intermittent Hypoxia Invited Review: Physiological and pathophysiological responses to intermittent hypoxia

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Physiological and Genomic Consequences of Intermittent Hypoxia Invited Review: Respiratory plasticity following intermittent hypoxia: developmental interactions

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2015

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.00235.2015